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 Mycobacterium tuberculosis

Posted By Admin    on 28-08-2021    Comments (10)

Morphology & Identification:
Thin straight rods 0.4*3μm.
Constituents of tubercle bacilli:
Cell wall 
a) Lipids - Mycolic acids long chain fatty acids (78-90C) waxes, Phosphatides.
b) Muramyl dipeptide (from PG) + mycolic acids ->Granuloma.
c) Phospholipids – Caseous necrosis.
d) Lipids – acid fastness.
e) Serpentine cords – AFB (acid fast bacilli) parallel arrangement cord formation- virulence cord factor (trehalose-6, 6’- dimycolate) – inhibits migration of leucocytes, - chronic granuloma. 

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