Microkalanjiyam

Bacterial,viral,fungal and parasite etiology

Posted By Admin on 19-12-2021 Comments (10)

INFECTIONS OF THE GENITAL TRACT

1.Genital tract consists of external and internal genitalia in both the sexes

2.External genitalia â€“penis and labia

3.Internal genitalia â€“male â€“testes, epididymis,seminal vesicles ,and urethra,prostate

4.Female â€“ ovaries,fallopian tubes,uterus,uterine cervix and vagina with its accessory glands

URETHRITIS AND CERVICITIS

1.Most common STI is Chlamydia trachomatis

2.Men â€“ pain on urination and urethral discharge (urethritis)

3.Women â€“ mucopurulent cervicitis ,acute urethritis â€“ PID â€“inflammatory scarring of fallopian tubes â€“ infertility and ectopic pregnancy

GENITAL ULCER DISEASE

1.Herpes simplex is commonest

2.Vesicular lesion with an erythematous base on glans penis,vulva ,perineum,buttocks or cervix

3.Vesicles are painful â€“ulcerate â€“ systemic symptoms with bilateral inguinal lymphadenopathy

Herpes virus

Important properties

Virion : spherical, 150-200nm in diameter(icosahedral)

Genome : ds DNA, linear

Proteins : >35

Envelope : viral glycoproteins, Fc receptors

Replication : Nucleus

Outstanding Characteristics

Envelope many enzymes

Establish latent infections

Reactivated in immunosuppressed hosts

Cancer causing

Classification

Herpesviriniae

Î±- HSV1, HSV2, VZV- Neurons

Î²-CMV, HH6, HH7 -glands, kidneyslymphoid tissue

Î³ - EBV , KSHV - lymphoid tissue

HSV

HSV1-saliva

HSV2-sexually -restriction enzyme analysis of viral DNA

Pathology

Cytolytic infections

Necrosis of infected cells with inflammatory response

Ballooning of infected cells

Cow dry type A intranuclear inclusion bodies

Margination of chromatin

Formation of multinucleated giant cells

MicroKalanjiyam

BACTERIOLOGY

Bacterial,viral,fungal and parasite etiology

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