Microkalanjiyam

case based series - Toxoplasma

Posted By Admin on 07-11-2021 Comments (10)

A 28 year old primi (fond of cats) ,5 months of gestation,complaints of fever,headache ,myalgia,enlargement of cervical lymph nodes.She has cleaned her cat's litter box 1week before without proper precautions.How will you manage her?Is there any risk for fetus?

1.It is probably a case of Toxoplasmosis caused by Toxoplasma gondii which is an obligate intracellular parasite affecting reticuloendothelial cells,muscle cells and intestinal epithelium

2.only protozoan where all the stages are infective - tachyzoite,bradyzoite and oocyst

3.Cats are definitive hosts

4.Humans and other warm blooded animals are intermediate hosts

5.trophozoite(tachyzoite) -crescent shaped - 7x3 Î¼m in size ,it invades any nucleated cell and multiplies asexually by endodyogeny or internal budding

6.Tissue cyst (bradyzoites) - chronic phase of infection,occurs in muscles,brain and other various organs,cyst size is 10 to 200 Î¼m

7.oocyst - formed in intestine of cats - after fertilization - zygote forms - oocyst with sporoblast divides into 2 sporocyst each containing 4 sporozoites .mature oocyst containing eight sporozoites is the infective form

MicroKalanjiyam

CASE BASED SERIES

case based series - Toxoplasma

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