Microkalanjiyam

definition ,classification,epidemiology,pathogenesis,microbiology

Posted By Admin on 05-11-2021 Comments (10)

Infective endocarditis is a microbial infection of endocardium ,generally of a heart valve or valves ,but chordae tendinae or at the site of a septal defect or other congenital abnormalities

Classification : acute,subacute or chronic - related to usual course of untreated disease,

Acute form - fulminating infection,high fever,severe malaise ,leukocytosis ,rapid destruction of heart valves.Virulent organisms - Staphylococcus aureus,Streptococcus pneumoniae ,Streptococcus pyogenes,Neisseriae gonorrhoeae without treatment - fatal,death within 6 weeks

Subacute form - infection with unspecific clinical findings and indolent course with death from the disease occurring after 6 weeks to 3 months.

Chronic form - occurring after 3 months and upto 2 years

Epidemiology - Rheumatic heart disease ,congenital heart disease ,arteriosclerotic disease - structural damage - turbulence of blood flow - endocardial damage

-idiopathic hypertrophic subaortic stenosis

mitral valve prolapse ,mitral valve regurgitation

haemodialysis shunts ,intracardiac pacemaker wires ,central venous catheters

Nosocomial infective endocarditis -

1.intravascular access for haemodynamic monitoring

2.administration of fluids

3.long term hyperalimentation and dialysis

4.advanced age ,surgical wounds ,genitourinary instrumentation,major abdominal surgery,implantation of prosthetic valves and cardiac devices,major burns

can affect both previously normal and damaged heart valves as well as prosthetic heart valves

Staphylococcus aureus in native valve endocarditis

Staphylococcus epidermidis - foreign body endocarditis

Fungal endocarditis - infected intravenous catheters

MicroKalanjiyam

general microbiology

definition ,classification,epidemiology,pathogenesis,microbiology

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